This involves placing the liquid underneath the tongue and letting it sit for 10-15 seconds prior to swallowing. Such placement enables contact with the mucus membrane , thus providing a more direct route of entry into the bloodstream. One dosage of LGD 4033 is sufficient each day. Taking it on a full or empty stomach will not affect its biological availability. LGD 4033 (Ligandrol) mg for mg is the most potent SARM on the market, high dose rad 140.According to the World Anti-Doping Agency (WADA), athletes are strictly prohibited from using Ligandrol and other SARMs, high dose rad 140.